Electronic Journal of Polish Agricultural Universities (EJPAU) founded by all Polish Agriculture Universities presents original papers and review articles relevant to all aspects of agricultural sciences. It is target for persons working both in science and industry,regulatory agencies or teaching in agricultural sector. Covered by IFIS Publishing (Food Science and Technology Abstracts), ELSEVIER Science - Food Science and Technology Program, CAS USA (Chemical Abstracts), CABI Publishing UK and ALPSP (Association of Learned and Professional Society Publisher - full membership). Presented in the Master List of Thomson ISI.
2020
Volume 23
Issue 3
Topic:
Biotechnology
ELECTRONIC
JOURNAL OF
POLISH
AGRICULTURAL
UNIVERSITIES
Robak M. 2020. WHY SOME YARROWIA LIPOLYTICA STRAINS SECRET CITRIC ACID TO THE MEDIUM?
DOI:10.30825/5.ejpau.188.2020.23.3, EJPAU 23(3), #01.
Available Online: http://www.ejpau.media.pl/volume23/issue3/abs-01.html

WHY SOME YARROWIA LIPOLYTICA STRAINS SECRET CITRIC ACID TO THE MEDIUM?
DOI:10.30825/5.EJPAU.188.2020.23.3

Ma│gorzata Robak
Department of Biotechnology and Food Microbiology, Wroc│aw University of Environmental and Life Sciences, Poland

 

ABSTRACT

Despite many studies, the “check points” of metabolic regulation of citric acid (CA) secretion by the yeasts Y.lipolytica still remain unknown. In this manuscript, some possible aspects of strain dependent secretion as well as CA metabolism regulation were discussed. Keys enzymes’ activities, substrate concentration, affinity of the uptake systems, intracellular CA concentration and strains abilities were the main points taken into consideration. The direction for the future studies emerged from this review, mainly connected to cellular and mitochondrial citrate transport systems and cellular substrates transporters (glucose, fructose, glycerol, ethanol and acetate), give promising starting point for future efficient strain development.

Key words: Yarrowia lipolytica, citrate synthase, intracellular CA, glucose consumption, RAPD.


Ma│gorzata Robak
Department of Biotechnology and Food Microbiology,
Wroc│aw University of Environmental and Life Sciences, Poland
Che│mo˝skiego 37/41
51-630 Wroc│aw
Poland
email: malgorzata.robak@up.wroc.pl

Responses to this article, comments are invited and should be submitted within three months of the publication of the article. If accepted for publication, they will be published in the chapter headed 'Discussions' and hyperlinked to the article.