Electronic Journal of Polish Agricultural Universities (EJPAU) founded by all Polish Agriculture Universities presents original papers and review articles relevant to all aspects of agricultural sciences. It is target for persons working both in science and industry,regulatory agencies or teaching in agricultural sector. Covered by IFIS Publishing (Food Science and Technology Abstracts), ELSEVIER Science - Food Science and Technology Program, CAS USA (Chemical Abstracts), CABI Publishing UK and ALPSP (Association of Learned and Professional Society Publisher - full membership). Presented in the Master List of Thomson ISI.
2014
Volume 17
Issue 1
Topic:
Veterinary Medicine
ELECTRONIC
JOURNAL OF
POLISH
AGRICULTURAL
UNIVERSITIES
Krzy瞠wska-M這dawska A. , Max A. , Bartyzel B. 2014. INFLUENCE OF GONADECTOMY ON SERUM FT4 CONCENTRATIONS IN MALE AND FEMALE DOGS, EJPAU 17(1), #01.
Available Online: http://www.ejpau.media.pl/volume17/issue1/abs-01.html

INFLUENCE OF GONADECTOMY ON SERUM FT4 CONCENTRATIONS IN MALE AND FEMALE DOGS

Alicja Krzy瞠wska-M這dawska1, Andrzej Max2, Bart這miej J. Bartyzel3
1 Department of Small Animal Diseases with Clinic, Warsaw University of Life Sciences (SGGW), Poland
2 Department of Small Animal Diseases with Clinic, Warsaw University of Life Sciences - SGGW, Poland
3 Department of Morphological Sciences, Warsaw University of Life Sciences - SGGW, Poland

 

ABSTRACT

The aim of this study was to compare the concentrations of free thyroxine (fT4) in castrated and non-castrated male as well as female dogs. Gonadal resection deprives the body of the primary source of hormones secreted by these organs. It may result in endocrine dysfunctions and among them particularly on thyroid level. Such relationships were reported in rodents, in dogs, however, they are poorly recognized. Dogs (n=124) without clinical signs of hypothyroidism or dermatological changes were divided into four groups: intact bitches, n=22, spayed bitches, n=45, intact males, n=26, and castrated males, n=31. The concentration of fT4 was measured by radioimmunoassay using commercial test for the quantitative determination of hormone in human serum. The average values in gonadectomized males and females was lower as compared to intact animals (p<0.05). In addition, in bitches a statistically significant effect of time that has elapsed from castration was observed. The time from castration was longer, the fT4 concentration was lower. In conclusion, the results indicate the enhanced risk of hypothyroidism in castrated dogs of both sexes. Additional studies are needed to recognize the influence of gonadectomy on thyroid gland on morphological, histological and functional levels.

Key words: dog, gonadectomy, ovariectomy, orchiectomy, fT4.


Alicja Krzy瞠wska-M這dawska
Department of Small Animal Diseases with Clinic, Warsaw University of Life Sciences (SGGW), Poland


Andrzej Max
Department of Small Animal Diseases with Clinic, Warsaw University of Life Sciences - SGGW, Poland


Bart這miej J. Bartyzel
Department of Morphological Sciences,
Warsaw University of Life Sciences - SGGW, Poland
Nowoursynowska 159, 02–776 Warsaw, Poland
Fax: +48 22 59-362-18
email: bartlomiej_bartyzel@sggw.pl

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