Available Online: http://www.ejpau.media.pl/volume1/issue1/veterinary/abs-06.html
THE INFLUENCE OF ALPHA-ADRENERGIC RECEPTORS ON UTERUS MYOELECTRICAL ACTIVITY IN SHEEP NON - SENSITISED AND SENSITISED WITH STILBOESTROL
Józef Dejneka, Dionizy Zięba, Stanisław Raułuszkiewicz
The research was conducted on 7 inter-breed hybrid sheep, at the age from 10 to 48 months and of the body mass of 32-47 kg, which had bipolar electrodes implanted to the uterus shank and horns. The registration of uterus myoelectrical activity was performed on non-sensitised sheep and 24-48 hours after stilboestrol sensitisation, with the use of electroencephalograph. After recording the output activity, the sheep were administered in continuous infusion: adrenaline – agonist of alpha and beta – adrenergic receptors in the dose of 0.12-0.18 μg · kg-1 · min-1; detomidin – agonist of alpha-adrenergic receptors in the dose of 0.1 – 1.1 μg · kg-1 · min-1; phenylephryn – agonist of alpha1-adrenergic receptors in the dose of 2.1 – 2.9 μg · kg-1 · min-1; xylasine – agonist of alpha2-adrenergic receptors in the dose of 0.5 – 4.0 μg · kg-1 · min-1; prazosin – antagonist of alpha1
Key words: sheep, uterus, myoelectrical activity, alpha – adrenergic receptors.